{"id":4413,"date":"2018-04-12T18:53:07","date_gmt":"2018-04-12T17:53:07","guid":{"rendered":"http:\/\/sea4us.pt\/?page_id=4413"},"modified":"2020-08-12T18:53:04","modified_gmt":"2020-08-12T17:53:04","slug":"sea4pain","status":"publish","type":"page","link":"https:\/\/sea4us.pt\/en\/sobre-nos\/projects\/sea4pain\/","title":{"rendered":"Sea4Pain"},"content":{"rendered":"\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t
\n\t\t\t\t
<\/div>
\n\n
\n\t\"LogosSea4Pain\"\n<\/div>\n\n<\/div><\/div><\/div><\/div>
<\/div><\/div><\/div>
\n
\n\t
<\/h6>\n

Sea4Pain<\/u><\/h1>\n \n
Development of a novel analgesic for chronic pain from marine-derived compounds<\/h5>\n \n
\n

Programme <\/strong>| Horizon 2020<\/p>\n

Call<\/strong> | H2020-EIC- SMEInst-2018-2020 (SME Instrument)\nTopic<\/strong> | EIC-SMEInst-2018-2020\nType of action <\/strong>| SME-1<\/p>\n

Project ID\u00a0<\/strong>| 815852\nProject acronym\u00a0<\/strong>| Sea4Pain<\/p>\nApproval Date\u00a0|<\/strong>\u00a023-03-2018\nStarting Date<\/strong>\u00a0|<\/strong>\u00a001-05-2018\nEnding Date\u00a0|<\/strong>\u00a030-09-2018\n\n \n

The Sea4Pain project will expand and define the development strategy for Sea4Us\u2019s \u201cDrug Discovery and Development Platform<\/a><\/strong>\u201d \u2013 a platform that applies novel biotechnological approaches to exploit marine derived compounds for the development of novel pharmaceuticals highly relevant for biomedicine.<\/p>\n

The first lab-based research results have clearly demonstrated the benefits of marine compounds in a series of pathologies, like chronic pain, and the huge potential of its derivate products in the health market. In particular, our innovative breakthroughs will lead to the development of a unique, high efficacy analgesic (ion channel blocker), with reduced toxicity and limited side-effects (Sea4Pain). This extremely innovative approach shows a differentiated mode-of-action (acting directly in the “pain switch”), that will give rise to a new class of pharmaceutical drugs with no expected adverse effects on the brain (currently being patented). The disruptive compound will block specific ion channels in pain-sensing neurons (Kv), for which there is no known modulator in clinical use, and ease the suffering of one fifth of the World’s population who constantly suffer from chronic pain.<\/p>\n

Sea4Pain will offer alternative treatments for patients suffering from moderate to severe chronic pain. Current drugs in the market (opioid derivatives and others) do alleviate pain but co-inflict important noxious effects (habituation, addiction, loss of drive) and great loss in quality of life. The global pain management drugs and devices market was estimated to be worth $38 billion in 2015 and reach $51 billion in 2022 at a CAGR of 4%.<\/p>\n \n

For more information, see the official SME Instrument website<\/strong><\/a>.\n<\/strong><\/p><\/blockquote><\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Sea4Pain   Development of a novel analgesic for chronic pain from marine-derived compounds   Programme | Horizon 2020 Call | H2020-EIC- SMEInst-2018-2020 (SME Instrument) Topic | EIC-SMEInst-2018-2020 Type of action | SME-1 Project ID\u00a0| 815852 Project acronym\u00a0| Sea4Pain Approval Date\u00a0|\u00a023-03-2018 Starting Date\u00a0|\u00a001-05-2018 Ending Date\u00a0|\u00a030-09-2018   The Sea4Pain project will expand and define the development strategy […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":3444,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-4413","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sea4us.pt\/en\/wp-json\/wp\/v2\/pages\/4413","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sea4us.pt\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sea4us.pt\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sea4us.pt\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/sea4us.pt\/en\/wp-json\/wp\/v2\/comments?post=4413"}],"version-history":[{"count":12,"href":"https:\/\/sea4us.pt\/en\/wp-json\/wp\/v2\/pages\/4413\/revisions"}],"predecessor-version":[{"id":5606,"href":"https:\/\/sea4us.pt\/en\/wp-json\/wp\/v2\/pages\/4413\/revisions\/5606"}],"up":[{"embeddable":true,"href":"https:\/\/sea4us.pt\/en\/wp-json\/wp\/v2\/pages\/3444"}],"wp:attachment":[{"href":"https:\/\/sea4us.pt\/en\/wp-json\/wp\/v2\/media?parent=4413"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}